ABSTRACT
Objective: To develop a efficient management system of medical equipment through utilized informational and intelligent technique in achieving scientific management of whole life cycle of medical equipment so as to enhance the operating efficiency of hospital. Methods: Through combined the existing management model of medical equipment and experience of hospital, and utilized many kinds of program languages to develop a software, and then to test and improve it in the interior of hospital. Results: The developed management system of medical equipment was able to implement accurate and efficient management throughout the processes of whole life circle, included of purchase, technique, economic calculation, quality control, risk assessment and disposition of scrapped equipment, of medical equipment of hospital. Conclusion: Management system of medical equipment is powerful tool and assistant of the decision maker of hospital, management department of medical equipment and the department of using equipment.
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the protective effects of natakalim against rat aortic vascular endothelial cells (RAVECs) injuries induced by hypoxia and its mechanisms.</p><p><b>METHODS</b>Selecting RAVECs as a cell model injured by hypoxia, these RAVECs were divided into 5 groups: i.e. control group, hypoxia group, natakalim low, medium and high group. The cell survival rate was determined by MTT assay, con was measured using Griess Assay, RT-PCR was used to examine t he expression of intercellular adhesion molecule-1 (ICAM-1), vascular endothelial growth factor (VEGF), endothelin-1 (ET-1) mRNA in RAVEC.</p><p><b>RESULTS</b>Natakalim could reverse hypoxia-induced changes in endothelial cell function, including increased endothelial cell survival rate and level of NO concentration, significantly inhibited the hypoxia-induced endothelial ICAM-1, ET-1, VEGF mRNA expression levels increased.</p><p><b>CONCLUSION</b>Natakalim have protective effects on hypoxia-induced changes in endothelial cell function, increasing of permeation, excess expression of cell adhesion molecules.</p>